Palmoplantar keratoderma has a certain genetic predisposition, and women may also inherit this disease.

Palmoplantar keratoderma is an autosomal dominant genetic disorder caused by a gene mutation, so women can also be affected. If there is a family history of the condition, genetic testing is recommended to understand your risk and to consult a doctor for appropriate treatment.

In addition, environmental factors and drug side effects can also lead to palmoplantar keratosis, especially in people who are exposed to chemicals or certain medications for extended periods. These factors can cause thickening of the stratum corneum, resulting in symptoms such as roughness and dryness on the palms and soles.
For patients with palmoplantar keratoderma, it is important to avoid using harsh detergents and cosmetics, keep the skin moisturized, and apply moisturizing agents such as urea cream or salicylic acid ointment as prescribed by a doctor. Regularly check for skin changes and seek medical attention promptly if any abnormalities are observed.