When urticaria flares up, some topical medications can be used to help relieve symptoms. It is generally recommended to use calamine lotion or mild steroid cream under the guidance of a doctor, while also taking oral antihistamines. This can quickly reduce itching and wheals.

The specific handling method can be selected based on different situations:

1. For mild itching with few wheals, you can first apply calamine lotion, which has a cooling and antipruritic effect and is less irritating to the skin.
2. If redness, swelling and itching are obvious, short-term use of a mild steroid cream such as hydrocortisone cream can help reduce the inflammatory response, but it is not advisable to use it for a long time or over a large area.
3. If the rash is widespread or recurs frequently, oral antihistamines such as loratadine or cetirizine are usually required. These medications can control allergic reactions from the inside.
It's important to note that topical medications primarily relieve surface symptoms. If hives flare up frequently or are accompanied by difficulty breathing, seek medical attention promptly. Avoid scratching your skin, wear loose-fitting cotton clothing, minimize hot water washing, and record and avoid potential triggers such as food and environmental factors to help control recurrence.